The X-Letter 33 has been published. In this issue of the SystemsX.ch print magazine, we highlight the central role that technology plays in systems biology research.
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Super-resolution imaging of multiple cells
Single-molecule localization microscopy (SMLM) techniques have been established as important tools for the study of cellular features with resolutions of the order of 10 nm. However, these techniques are limited by a highly constrained field of view (FOV) as well as field-dependent image resolution. Researchers from the EPF Lausanne have developed a low cost microlens array (MLA)-based epi-illumination system—flat illumination for field-independent imaging (FIFI)—that can efficiently and homogeneously perform simultaneous imaging of multiple cells with nanoscale resolution. This research was supported by a SystemsX.ch Transition Postdoc Fellowship. More information on Nature online»
Broadly neutralizing HIV antibodies pave the way for vaccine
A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types of HIV that circulate worldwide. Researchers from the University of Zurich and University Hospital Zurich now reveal which factors are responsible for the human body forming such broadly neutralizing HIV antibodies, thereby opening new avenues for the development of an HIV vaccine (Image: David S. Goodsell, RCSB PDB).This research was supported by the SystemsX.ch RTD Project AntibodyX.
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Machine Learning Course
Do you have more data than you know what to do with? Would you like to learn how to identify patterns in it? Machine learning is a useful tool for finding interesting patterns in data without the need for extensive programming. The five-day course “Machine learning for bioinformatics and computational biology” will take place from November 21-25, 2016 at the University of Zurich.
More information and registration »