BIPs 2011

Bridge 2 Industry Projects Approved in 2011:

Title: Structure-phenotype Relationship of Drugs: the Microtubule Cytoskeleton as a Model System
Applicants: Dr. Michel Steinmetz (PSI), Dr. Andrea Prota (PSI)
Industry Partner: Dr. Heidi Lane, Basilea Pharmaceutica
Scientific Fields/Keywords:

  • Structural Biology 
  • Biochemistry 
  • Cell Biology 
  • Microtubule 
  • X-ray crystallography

Title: SpidX: An Integrated Platform for Spider Venomics
Applicants: Dr. Frédérique Lisacek (SIB), Prof. Wolfgang Nentwig (UniBE)
Industry Partners: Dr. Reto Stöcklin, Atheris Laboratories, and Dr. Roman Mylonas, GeneBio SA
Scientific Fields/Keywords:

  • Spider toxins / Antivenoms
  • Bioinformatics / EST
  • Drug Discovery
  • Insecticides
  • Mass Spectrometry / Proteomics
  • Transcriptomics

Title: A Systems Biology Approach to Identify Instructive 3D Stem Cell Microenvironments
Applicant: Dr. Matthias Lutolf (EPFL)
Industry Partner: Dr. Simone Rizzi, QGel SA
Scientific Fields/Keywords:

  • Embryonic stem cells
  • 3D artificial extracellular matrix
  • Cell-based assays
  • High-throughput screening
  • Tissue engineering
  • Tissue/disease modeling

Title: System-wide Identification of Novel MALT1 Substrates
Applicant: Dr. Ulrich Auf dem Keller (ETHZ)
Industry Partner: Dr. Samu Melkko, Novartis
Scientific Fields/Keywords:

  • Biochemistry
  • Proteomics
  • Protease
  • Substrate
  • Lymphoma 

Title: Real-time Analysis of the Steady State Levels of Riboflavin and Pathway Intermediates in Cell Free Extracts Upon Perturbation of the Rib Enzyme Configuration - a Basis for a Rational Design of a Multienzyme Network
Applicant: Prof. Dr. Sven Panke (ETHZ)
Industry Partner: Dr. Hans-Peter Hohmann, DSM
Scientific Fields/Keywords:

  • Systems Biotechnology
  • Real-time mass spectrometry
  • Vitamin production
  • Pathway
  • Optimization


Department program of SNF